libro azul de infectologia pediatrica 2012 pdf

International Nuclear Information System (INIS)

On the other hand, the severity of our patient's neurological and psychiatric symptoms correlates well with the severity of her hyperostosis frontalis interna and the cortical atrophy.īone metabolic activity in hyperostosis cranialis interna measured with 18F-fluoride PET Endocrine or nutritional disorders may have led to an altered bone metabolism with frontal bone apposition. Metabolic and endocrine dysfunctions should be interpreted not only as isolated components of the syndrome, but also as the reason behind its pathogenesis. A case of full penetrance of Morgagni-Stewart-Morel syndrome is reported, presenting many of the clinical features described in the literature. Possible pathophysiological mechanisms underlying both the headache and the hyperostosis frontalis interna are discussed. In this clinical case seminar, we summarize the current understanding of the association between hyperostosis frontalis interna and Morgagni-Stewart-Morel, based on a MEDLINE search (case reports, original articles, and reviews published between 19) on this topic. These findings, associated to the metabolic and neuropsychiatric pattern of the patient, are consistent with a high penetrance of Morgagni-Stewart-Morel syndrome. On instrumental examination she was found to have extensive frontal hyperostosis and cortical atrophy. A 75-year-old woman presented with severe frontal headache and a history of psychotic disorders. The possible cause-effect relationship of these associations remains uncertain. Morgagni-Stewart-Morel syndrome is defined as the presence of hyperostosis frontalis interna, variably associated with metabolic, endocrine, and neuropsychiatric disorders. These two skeletons are the subject of an analysis which may possibly throw some new light on the controversial and continually disputed nature of this illness.įull penetrance of Morgagni-Stewart-Morel syndrome in a 75-year-old woman: case report and review of the literature.Īttanasio, Francesca Granziera, Serena Giantin, Valter Manzato, Enzo The similarity of their morphological and metrical traits indicates that they could be related, and suggests that HFI is likely to have a genetic base. These were two female skeletons from the 16th century Dominican Church in Raciborz (Southwest Poland). Two cases of thickening of the internal tables of the frontal bones ( hyperostosis frontalis interna, (HFI)) have been examined. Hyperostosis frontalis interna, a genetic disease?: Two medieval cases from Southern Poland.

We present a novel case of migraine headache in a gentleman with Klinefelterâ€™s syndrome and HFI, along with a discussion of possible pathophysiologic mechanisms underlying both the headache and the HFI. Hyperostosis frontalis interna (HFI) has been reported in older women, but reports in men are rare. Headache in a patient with Klinefelterâ€™s syndrome and hyperostosis frontalis interna

Libro azul de infectologia pediatrica 2012 pdf